P2RY4
Neste artigo, exploraremos o tópico P2RY4 em profundidade, abordando suas origens, desenvolvimento e relevância hoje. Desde o seu surgimento, P2RY4 tem despertado o interesse de acadêmicos, especialistas e do público em geral, suscitando debates, reflexões e avanços em diversos campos. Ao longo dos anos, P2RY4 tem-se revelado um tema de grande importância, tanto pelo seu impacto na sociedade como pela sua influência em diferentes áreas do conhecimento. Através desta análise abrangente, procuraremos compreender o significado de P2RY4 e o seu papel num mundo em constante mudança.
No campo da biologia molecular, P2RY4 é uma proteína que pertence ao grupo dos receptores P2Y e que, em seres humanos, é codificada pelo gene P2RY4.[1][2]
Referências
- ↑ Communi D, Pirotton S, Parmentier M, Boeynaems JM (fevereiro de 1996). «Cloning and functional expression of a human uridine nucleotide receptor». J Biol Chem. 270 (52): 30849–52. PMID 8537336
- ↑ «Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4»
Leitura de apoio
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- Nicholas RA, Watt WC, Lazarowski ER; et al. (1996). «Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.». Mol. Pharmacol. 50 (2): 224–9. PMID 8700127
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. PMID 9535005. doi:10.1038/sj.bjp.0701665 - Brinson AE, Harden TK (2001). «Differential regulation of the uridine nucleotide-activated P2Y4 and P2Y6 receptors. SER-333 and SER-334 in the carboxyl terminus are involved in agonist-dependent phosphorylation desensitization and internalization of the P2Y4 receptor.». J. Biol. Chem. 276 (15): 11939–48. PMID 11114308. doi:10.1074/jbc.M009909200
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